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The Wim Hof breathing method boosts immunity

3/5 evidence score1 peer-reviewed study reviewedLast checked August 21, 2026

Educational, not medical advice. Always consult a qualified healthcare provider before changing your diet, supplements, or routine. Full disclaimer.

What the science says

Wim Hof breathing training is not proven to boost immunity against infections - what the one relevant study actually shows is that trained people can partly switch off their body's inflammatory response on command. In that 2014 trial, 24 volunteers trained in the method's breathing, cold exposure and meditation were injected with a bacterial toxin, and the trained group produced about 50% lower levels of inflammation-signalling proteins, with less fever, than untrained volunteers. That is a real finding about controlling the body's stress response, but it is not proof the method prevents illness or strengthens long-term immunity, and it comes from a single small study.

Full analysis

In a 2014 trial published in PNAS, the Proceedings of the National Academy of Sciences (a long-running peer-reviewed journal published by the United States national science academy), researchers trained 24 volunteers in the Wim Hof method - breathing, cold exposure and meditation - then injected everyone with a bacterial toxin that normally triggers fever-like symptoms. The trained group showed about 50% lower levels of two inflammation-signalling proteins (TNF-alpha and IL-6), plus less fever, than untrained volunteers.

This shows people can, with training, voluntarily dial down part of the immune response - something researchers had not thought possible. It is a well-designed trial, but still just one trial, testing an acute (short-term) reaction to an injected toxin, not everyday resistance to illness.

The results do not show the method prevents infections, improves the immune system's ability to detect abnormal cells such as cancer, or gives any lasting immune benefit. Dampening inflammation on command could even work against the body, since inflammation also helps clear out germs.

Cold exposure, breathing exercises and meditation each have separate evidence for general health. What this study demonstrates is control over short-term stress and inflammation, not a stronger immune system against disease.

Key studies

The studies that carry the verdict.

[1]Voluntary activation of the sympathetic nervous system and attenuation of the innate immune response in humans

Kox M et al. · PNAS · 2014

In a small trial, volunteers trained in the Wim Hof method could partly shut down their body's inflammatory response to a bacterial toxin, producing about 50% lower levels of inflammation-signalling proteins than untrained volunteers.

View paper

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